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Given that GSSG was significantly accumulated in the A2ARi-treated activated CD8 + T cells (Figure 3H), we hypothesized that the T cell ferroptosis induced by A2ARi could be due to the enhanced GSH usage and subsequent increased GSSG accumulation

This triad promotes the release of pro-inflammatory cytokines and induces a predominant Th1-mediated immune response characteristic of Hashimotos thyroiditis (HT)

Ferraz et al

Dermatologic Surgery, 51(2), 198-207

Strategic synthesis: navigating the landscape of PLGA nanocarriers in CRC therapy The exploration of PLGA nanocarriers in colorectal cancer therapy has unveiled a diverse array of strategies aimed at overcoming two major clinical challenges: chemoresistance and poor drug bioavailability

doi: 10.1016/j.pbb.2022.173492 164 BakasTvan NieuwenhuijzenPSDevenishSOMcGregorISArnoldJCChebibM